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The Health Professional's Guide to Popular Dietary SupplementsAmerican Dietetic Associati. 2022
Twenty-nine new dietary supplements have been added to this edition! This guide comprehensively explores the media claims, drug-supplement interactions, dosage information and relevant research for more than 100 of today's most popular dietary supplements. Completely revised, updated, and indexed information is provided for dietetics professionals and their clients. Written by industry experts, this guide's recommendations are reliable and backed by credible clinical research.
Since I have liver disease, I have to be very careful about what I consume in order to avoid a painful flare-up. When I first started taking this product, I noticed a dull, minor pain in the middle of my liver, which startled me enough to stop taking it for fear it would get worse. However, later I found out that when you first start taking a product with milk thistle included, it can cause minor pain like this as a sign that the liver is beginning to detox itself. If I had continued taking it, probably the pain would have subsided and the benefits would have come out. I will be trying again soon, and stick with it long enough to see if it really works.
I take this in addition to DIM to aid in prevention of hormonal acne. Only posting pictures to prove how well this product along with DIM works, in hopes of helping other fellow sufferers. These pictures were taken less than 2 months apart.
Milk thistle is amazing.I started taking it because I took a couple of rounds of antibiotics and started to eventually feel side effects. My gut was pretty messed up. When I told my doctor about this, guess what he wanted to do? Place me on another round of antibiotics. Surprise, surprise. So then I decided to take the plunge and went to see a naturopath, or what my friends like to call a hippie dippy, witch doctor. Haha. And I felt like the naturopath gave me more insight to my body than ever before. He recommended a couple of herbs and milk thistle was one of them.I’m so glad I started taking this. I’ve read up on it a lot and it has crazy benefits. The thing about this herb is it’s not like you’ll notice a night and day difference right away or even within a few weeks. It’s a difference that you’ll notice big time in the long run…if that makes sense. It helps to clean the body out as a whole and once your liver is functioning well (milk thistle’s main superpower is liver detoxification), everything else will function better too.This is a side note….but I did notice something funny/interesting about this herb that I didn’t really expect. So, when it comes to drinking alcohol, I’m a light weight and I’ve always been the person that feels the nasty hung-over effects in the morning, even with just 1 – 2 glasses of wine. But one day, I decided to take milk thistle about 2 hours before going out ….and I noticed I wasn’t feeling as “susceptible” to the effects of alcohol as I normally do. I mean…I wouldn’t recommend using it to be able to drink more or anything, but if you’re a cheap drunk, you get the point. 😉 Then the next morning….to my surprise…. I woke up feeling great! Hell, I even went for a run….it was awesome! Milk thistle contains silymarin and silybin, antioxidants that are known to help protect the liver from toxins, including the effects of alcohol.It’s also shown to decrease, or even reverse, damage to the liver that’s been caused by prescription medications, antibiotics, pollution, heavy metals and so on. If you’re still undecided, I’ve included a bit more info about it below.It helps with:1. Liver Detoxification & Health It helps rebuild liver cells while removing toxins from the body that are processed through the liver. It’s effective at naturally reversing the harmful effects of alcohol, pesticides, jaundice, psoriasis, fatty liver, heavy metals in our water supply, pollution, and even poisons!The liver is actually our largest internal organ and is responsible for performing a number of essential detoxifying functions. Basically, if our liver is in bad shape, our whole body will be in bad shape. As a “blood purifier,” the liver needs to actively clean the blood each and every day in order to support nearly every system within our body.2. Helps Protect Against CancerMilk thistle seeds are a high source of the antioxidant flavonoid called silymarin. Silymarin is associated with decreasing the risk for cancer development by boosting the immune system, fighting DNA damage and reversing cancerous tumor growth.In 2007, after reviewing numerous studies involving milk thistle therapeutic treatments, researchers at the University of Minnesota found that:“There is strong preclinical evidence for silymarin’s hepatoprotective and anticarcinogenic effects, including inhibition of cancer cell growth in human prostate, skin, breast, and cervical cells.” (4)This antioxidant stimulates protein synthesis and changes the outside layer of healthy cells, keeping them protected from damage and mutation. It inhibits toxins from dwelling in the body; helps with cell renewal; and counteracts the harmful effects of pollutants, chemicals and heavy metals that can cause “free radical damage.”3. Can Help Lower High CholesterolMilk thistle benefits heart health and helps lower high cholesterol levels by lowering inflammation, cleaning the blood and preventing oxidative stress damage within the arteries.4. May Help Control or Prevent DiabetesOne 2006 study conducted by the Department of Pharmacology at the Institute of Medicinal Plants found that when diabetic patients were given silymarin extract over four weeks, their fasting blood glucose and insulin levels improved significantly compared to patients receiving a placebo.This is likely true because the liver is partly responsible for regulating hormones, including the release of insulin into the bloodstream. Insulin is responsible for managing blood glucose (sugar) levels in the blood, which is especially important for those with diabetes.5. Helps Prevent GallstonesMilk thistle benefits help support the endocrine and gastrointestinal systems by aiding in the production of bile and enzymes, on top of helping clean the blood. Milk thistle can help purify the body of metabolic waste, thereby regulating the function of the gallbladder, in addition to the kidneys and spleen.6. Boosts Skin Health healthy skin, showered clean skinMilk thistle is considered to be a potent inhibitor of UV-induced oxidative stress that can cause skin diseases like skin cancer. Research also suggests that applying silymarin found in milk thistle to the skin reduces skin damage caused by radiation treatment in patients who have had treatments for cancer.7. Has Anti-Aging EffectsBecause milk thistle’s antioxidants help prevent free radical damage throughout the body and remove pollutants and waste from the blood and digestive tract, it can actually slow the aging process. This is true on both the surface of your skin and also within your organs.8. Milk Thistle and GlutathioneSilymarin, the active ingredient in milk thistle, is an antioxidant that can protect against depletion of glutathione, which is a “master antioxidant” that’s extremely useful at helping prevent disease formation.Its biggest role is to help fight oxidative stress that leads to such diseases as cancer, diabetes, heart disease and neurodegenerative diseases. It can help prevent damage to important cellular components caused by reactive oxygen species, such as free radicals.Disclaimer: I was NOT given this product for free to review. I just really love this herb!
My mom asked to write this review, it may help others. About 3 years ago my mom had liver serious problems. At that time she was not able to get treatment with a specialist. Her physician said to take silymarin daily. Since there she hasn’t stopped taking it. And also about two, three times a week she has a green juice made with kale, spinach, cucumber, celery, beet, lemon, carrot, apple, ginger and turmeric root, and cilantro.She says, is it a lot of work? yeas, it is, but worth it. She just came from the doctor and she has a healthy liver.
This stuff works. Calms an upset stomach and stops you feeling sick. I know people swear by it as a hangover cure, but I am using it to counter side effect of medication I have to take,and it does stop me feeling nauseous
I ended up with fatty liver from years of alcohol abuse. I stopped drinking, but still had pain. I used Dr Tobias and Trunature, but still had some pain. I got these, taking them 3x a day…no pain, feel great, liver panel normal. Even if you are still drinking, milk thistle can help minimize/repair the damage…of course best to quit altogether. 5 stars
I was looking for a liver cleanse/detox that was easy to take and easy on my system. About a week into the treatment I started to notice a positive difference in digestion. $20 for 200 pills is great value. I take it in the evening few hours before bedtime. I’ll be adding this supplement to my daily routine.
This little bottle is a must for any all-inclusive holiday I overindulged as you do on these holidays.It doesn’t stop a hangover but takes away that sickly feeling which makes a big difference when you can eat the fried breakfast in the morning and keep it down definitely recommend this product.
DetoxificationWhy detoxification?There were many clues but the one I picked up on was the peculiar greyish-green color under my skin. I call them “liver spots” (they aren’t)The clue I wish I pursued came almost five years ago. I could no long detox alcohol very well. I’d drink ½ a glass, stay drunk for 2 hours then fall asleep and wake up hung over out the yin-yang. Everybody rejoiced because I gave up alcohol. Big problem solved eh? No one, not even the doctors stop to ask, what happened to all that alcohol dehydrogenase in the liver? When a doctor fails to take any action when you shows signs of impaired liver function, FIRE THEM!More clues. Suddenly my allergy medication Claritin started to work really really well for the first time in 20 years– 24 hours long as promised on the label. Cyp3A4 is the liver enzyme that metabolizes Claritin. In addition, I’m a fast metabolizer. Claritin hits fast and hard and wears off fast. So that 24 hour pill wears off after about 16-18 hours for me. Something is slowing down my production of another liver enzyme.Side note: Cyp3A4 and Cyp2D6 both metabolize Claritin but I don’t have any Cyp 2D6 because I don’t metabolize narcotic medications.Luckily for me, the liver regenerates.How do you track progress as you detox?It helps if one of your toxic (?) compounds has a gray-green tint and collects under your skin. How do I know it’s not a normal pigment ? Well if I rub my skin for about 5 minutes, I can get the pigment to move away leaving a pink spot on my skin.I’m pretty sure I had a Candida infection. One of the products to eradicate the Candida – a bunch of enzymes that attack it, left a growing gray-green tint under my skin. I’ve had this stuff under my skin for most of my life but faintly. It was most pronounced as a “moustache” on my upper lip. But now, the stain was growing until I only had two pinkish patches on my cheeks…. right above my lymph nodes.Aside from the visual are there other symptoms? Listless/low energy, burning sensation under the skin and in the muscle, patches of skin tender to the touch, irritability, shortness of breath without causeWell, the stain could be something from the Candida or it could be a by product of the enzymes. But I’m betting on the Candida because…Every time, I read about Candida, people recommend a detox program especially for the liver. Candida by-products and wastes are particularly rough on the liver. Additionally, my gut was down. Constant diarrhea means your body isn’t eliminating waste products efficiently. Or at all. But the gut recovered recently. I’m certified Candida-free. Now is the time to support the liver. And milk thistle is almost universally recommended. The silymarin in milk thistle helps 1) protect the liver (antioxidants protect the liver from free radical damage), 2) assists in liver function (stabilizes liver membranes, increases ability to filter toxins from blood), and 3) may regenerate the liver helping with recovery from cirrhosis and other types of liver disease/damage. The therapeutic dose varies – but 100 – 200 mg of silymarin is pretty standardDoes the milk thistle/silymarin work? Based on the color changes in my skin: the more silymarin I take, the cleaner my skin looks. I’ve tried anything from 500 to 1500 mg of this powder. I’ve tried to cook up a tincture (too much work, didn’t like the alcohol). If I stop taking the milk thistle for a week, the stain just starts piling up again. Whatever this stuff is, it’s been accumulating for months. I suspect a steady, rational approach with milk thistle would have this cleaned up in about six months.But let’s be systematic. It’s not just the liver. It’s all of the detoxification mechanisms in the body that are overwhelmed: Liver, lymph, skin & sweat glands, the gut, kidneys, bile and probably more that I don’t understand. It’s rather lengthy, if bored skip to the bottom under Results and then read the detox procedure below.1) Drink pure water. At least 1/2 gallon is the minimum. A gallon would be better. Supports all the organs. I do this normally so this ends up at the bottom here1a) Add juice from 1-4 lemons/8oz of cranberry juice/1 oz apple cider vinegar (not all at once!) to a gallon of water. The juice helps drain the lymph nodes and helps kidney function. Adding any one of these juices created a synergistic effect and the stain under the skin started to clear out faster.1b) Skin and sweat: heat therapy – hot (Epsom salt, baking soda or Toors mud) baths or showers, sauna’s. Foot baths are recommended for those who cannot take a bath. The key is to raise your core body temperature and sweat. For some toxins, this is the easiest way to expel it. Unfortunately for me, bathing & sweating does remove some of it and clear the skin fast but the heat just seems to draw out the internal mother lode and bring fresh stuff to the surface. It’s a bit discouraging to see more of this stuff after a particularly hot bath. Hot baths and cold showers (keep cold therapy short. It’s beneficial if it feels refreshing, if you’re shivering, you’ve gone too far) also trigger production of heat shock proteins. Toor’s mud is particularly good for a detox because it’s high in magnesium, calcium and sulfur. All three are beneficial if the body is toxic or stressed. You may wish to consider using a biomat (far infrared sauna) as well.2) Basic gut support (for the gut cleanse)a) use a quality fiber. I use WellbetX PGX because I’m diabetic but if you can’t afford it, glucomannan is very good.b) use a probiotic. Probiotics can be super specialized. Pick a formulation that is designed to address your issuesc) Use a resistant starch. Resistant starches resist digestion (by you), it is your helpful probiotics that digest this stuff. If you don’t want to use a lot of products, then pick this one. Bob’s Red Mill unmodified potato starch is the most concentrated form of resistant starch that is also readily available. Start SLOWLY, try 1/2 or 1 tsp and work your way up to 1 tbsp 3x per day. I’m a BIG fan of resistant starch. This stuff has got legs. It helps you at lower levels and it just keeps going.d) if you experience diarrhea, a tablespoon of arrowroot powder per day for a few days maybe helpful. Very few people have trouble digesting arrowroot powder, very low allergen potential, it works as a demulcent soothing the gut. It has also been shown in the laboratory and in real life to neutralize insect, toad, frog and plant poisons AND it was used as a early antiseptic/antibiotic – they packed poison wounds with this powder. But apparently no one has done clinical trials and therefore can’t even speculate on what’s happening in the gut. So I will – it’s a war in your gut. Bad and good bacteria alike put out toxins in an effort to prove Darwin right. Ya think something like arrowroot with it’s ability to neutralize all those other toxins might be up to it’s usual tricks in your gut? That’s the reason why it’s soothing? Plus it’s an antiseptic. Do you think a millennium of munching on arrowroot tubers might have… you know… done something to our gut microbiome? Therefore, our probiotics might be arrowroot resistant and those bad bugs unused to a diet of arrowroot get clobbered? At any rate, one tbsp of arrowroot seem to prevent diarrhea for me. For about 3 hours it felt like nothing much. Then from the 3-24th hours, there was a nice soothing sensation and little pops of gas that tootled on. From the timing, the action is all in the large intestine. It works on my present mild diarrhea.3) Liver support – milk thistle – highly recommended. Progress using any of these methods is accelerated with the milk thistle.4) Kidney support – the acid in the lemon/cranberry juice helps the kidneys function better. A gallon of water is serious kidney support5) Lymphatic support – the increased water & lemon juice helps drain the lymph nodes faster6) Bile – milk thistle support bile production by supporting the liver.7) Support glutathione production. Glutathione is the master enzyme that regenerates ALL your antioxidant enzymes. Glutathione is made up of N-acetyl-L-cysteine (NAC). You can purchase this. Glutamate, I purchase this as a powder. Glutamate can only be absorbed on an empty stomach. So I dissolve in water and drink when I wake up in the middle of the night. Finally, glycine. I don’t worry about this too much but it is readily found in collagen (buy as a powder or drink bone broth). You can also buy glutathione but it’s not very bioavailable There are special methods to create bioavailable forms but it’s technical and you need special equipment.Why glutathione? Most toxic chemicals generate free radicals; your antioxidant enzymes mop them up. But if your glutathione is stripped then the war is over and you just lost.8) Alpha lipoic acid (ALA) – this is an antioxidant that is normally produced by the body and is found in the mitochondria. It is soluble in water AND fat. It can cross the brain-blood barrier. Normal therapeutic doses of ALA range from about 1200 mg to 1500 mg. Because it has a sulfur group, it is one of the few antioxidants that can bind mercury and stay bound. ALA is used to treat mercury poisoning (there is a special protocol). The levels suggested here are too low to treat mercury poisoning but they are sufficient to prevent mercury poisoning from regular everyday exposure.9) Other antioxidants – melatonin, Vitamin C (7-8 gms for optimal function), A, D and E, lycopene, lutein, ALA- detoxification can sometimes draw out stores of toxins from the fat and other organs especially heavy metals. Neutralize them with antioxidants. Choose a mix of antioxidants. Also make sure you have some that are fat soluble and others that are water soluble.10)vitamins in general: to restore normal function11) Focus on sulfur, magnesium, calcium and zinc. These are required for normal function and they are protective. Some will compete with toxins forcing the toxin out into the blood / other organ to be flushed. Unfortunately, they aren’t very bioavailable. For example, the zinc will block the absorption of magnesium. The easiest way to take them is separately. Or you can go very high end and get Hardy’s Essential Nutrients (it’s over $100 per month, you need to take 12 capsules daily but Hardy’s has the clinical trial data to back up their claims about bioavailable).12) Exercise. This item only just made it back to my list in the last six months. Before, I was so loaded up with toxins, that exercise made things worse. Two months ago, I would go for a 45 min walk and then be utterly listless for a week. Now, I can take a walk every day and it doesn’t affect me noticeably. That’s still not good. You’re supposed to feel good after a walk, not grateful that you made it back without danger of collapse.13)Food: The one food that I avoided religiously, yup, organ meats. I settled on chicken livers. Because liver has everything you need to support your liver. Old Chinese adage.RESULTSI started off the detox as simple liver support using milk thistle and lemon juiced in a gallon of water. I noticed the effect of the thistle/lemon addition within a few days. The stain under the skin was moving out faster but it was begin replaced almost as quickly.Separately, I’d been advised to try 1200 mg alpha lipoic acid a powerful antioxidant for my abnormally low energy. This led off into a entirely new line of inquiry about mitochondrial biogenesis. Suffice it to say there are many reasons to take ALA and I had all of them. And if I had to pick only a handful of antioxidants it would be CoQ10, ALA, resveratrol, melatonin, vitamin C, D. CoQ10, ALA and resveratrol for their versatility and power and the rest because they are cheap, powerful and versatile. And you’re gonna need to think about this because during a detox, there is no telling what you’ll stir up. Therefore every antioxidant becomes recommended to neutralize it. If you force me to trim this list down further, then I will recommend CoQ10 and ALA. CoQ10 because it’s so all purpose and ALA because it can detox some heavy metals (mercury and lead). But at this point, I will also recommend you avoid detox altogether.I noticed ALA had the peculiar effect of driving my energy up, way up and then I crashed around 4PM and felt like I couldn’t move again. I learned later that’s a common effect with ALA, it cleans up everything in sight, you feel great, then you feel lousy because it can also extract toxins from fat cells (a common place to stash your body’s trash). I found out I could mellow out the crash if I used more milk thistle than recommended – about 15 times more. Luckily I ran across another brand of milk thistle which was 30 times more concentrated. Their recommendations were exactly in tune with my needs, so I switched over to Jarrow. I ended up taking a capsule of milk thistle for every capsule of ALA (I take in 300 mg doses 4x per day).Smoothing out the ALA and beefing up the milk thistle had the effect of leaving me agitated, in mild pain, listless and irritable. But I was able to tolerate 45 minute walks, hot baths and other activities like building defenses to protect myself from my stalker (another story) without becoming limp from stirring up all that toxicity.So the protocol is able to keep up with the toxic sludge but why not increase the ALA and everything else too? It’s the rate of detoxification in the liver. The liver can handle only so much. If you start pulling stuff out of the fat too fast then it just has to go back in but not before it’s caused all sorts of trouble. Mercury is a great example. It gets stored away in fat and brain. ALA is one of the few antioxidants that does a good job with mercury but slowly.Finally, after about four months plus a bit, the first break came. I’d done my usual exfoliation and discovered long scratches in my skin that showed pink instead of more greyish-green. So something was killing the stuff from the inside.Update Nov. 3 – I seem to be cycling around to a higher energy again. The gray-green tint is definitely receding. I asked my doctors about this stuff and they both got so technical they started to mumble. I still don’t know what this is but both my docs said my detox protocol was the right way to go. There is no harm in it as long as I stay within recommended doses for the antioxidants. And yes, it’s a long, slow grind waiting for the situation to correct itself.Conclusion: something is working! But there’s more months of this still.
I suffer from PCOS and I was recommended to take these drops twice a day as I started to notice a decline in my skin which started to go patchy colours with lots of acne which really started to frustrate me as I couldn’t figure out how to get rid of it however after taking 10 drops, twice a day it all cleared up within 9 days!!Highly recommend!
Milk Thistle is an amazing herb. It’s brilliant for liver detox, constipation and even helps your heart and immune system. If you’re in a Paleo , high fat or even vegetarian diet, the liver usually needs some help as we rarely eat bitter foods ( eg watercress, endives, chicory leaves, dandelion leaves etc) which stimulate the bile in the gall bladder which then aids digestion by breaking down the food and fats etc. Milk Thistle does this very well and is well tolerated I imagine by most adults. Warning- start with a small dose , maybe 8-9 drops x2 daily and build up to more gradually as sudden deep detox can make you feel quite ill, with flu like symptoms, headaches, lethargy and nausea as the toxins flood your system . So slowly does it. Also make sure you drink at least a litre of water + to help flush the toxins out of the body. This product is good quality and if you research all the benefits I guess most of us would do well to take regularly.
Nice packaging, easy to swallow, keeping my liver nice and healthy! Would purchase again and probably will soon. Would recommend if you are looking for a decent Milk Thistle product for a good price. Buying these products from High Street retailers really hurts the pockets.
I take this with a few other supplements for my PCOS plus an added benefit… for my liver. I have experience occasional pain in my abdomen over the liver. I haven’t experienced any side effects with it. Very thankful for this product.
My GP advised me to purchase liver support after a cycle of meds. Prior to the purchase my skin appeared colourless and under my eyes were dark circles. A few weeks into supplementation I noticed a change in appearance including brighter appearance and zero dark circles. Great product, I now keep a bottle about the cabinet in the event of excessive drink or a mere detox effort. Love this product
Take large doses off pain killers, so wanted something to support liver and kidneys.
Healthy and organic , great value with the extra 40 pills provided .easy to swallow and virtually tasteless makes keeping your liver simple .Being Canadian owned and operated always makes me happy .
I was feeling pain in all my body, fibromyalgia pain alike. It look like I may had mecury poisoning, Awful, I just can’t keep going with my normal routines and I started to feel down. I made several researching and found this product. I took the chance and I do not regret it. I started feeling better and better every day!!! I’m doing all my activities with more energy and no pain. The only thing that you need to be aware of, is that this pill needs to go with lots of water, I feel very dehydrated every time. But I’m very happy for the results. I know that every single body works different, but this is my experience with this particular product. My hopes are that it works for you too!!!
I don’t often write reviews but I wanted to for this product!Some background- I am on a waiting list for a full hysterectomy due to fibroids in my uterus, and suffer from lots of pain during that time of the month. 6 months ago I started to have severe pain most days even when I was not on my period. I was taking pain killers for the first time in my life!By coincidence I read an article in a women’s health magazine talking about this herb and how wonderful it is for womens health, especially with what I’m going through and all the inflammation. I’ve taking a ton of supplements for various things over the years and nothing has had instant and noticeable effects like this! It has completely removed my pain in between periods and has also greatly decreased it during.I highly recommend!
Superb Milk Thistle drops. I started them in September 2019 with a liver function test result of 152. In January 2021 it is 82. This is the lowest it has been in 18 months. Normal liver function is below 55. So I’m very happy with the results and the product. I achieved these results on 20 drops a day.
Best company I’ve found for these ! Probably the best value for your money too. I spent so much time searching and a lot of the products require you to take 3 times a day and have less capsules per bottle. I like these because you only have to take 2 a day, and the serving size is actually 2 so you don’t have to divide it into separate servings. Easy for someone forgetful like me! But I honestly only take 1 a day in the mornings and it works just fine.
With something like this you don’t feel immediate results… if any at all. I have added Milk Thistle to my vitamin routine. I have some pretty severe GI issues with 2 autoimmune diseases… this product has not cause any flare ups. The pills are larger in size, but are not hard to swallow. Highly recommend!
Great product to protect the liver. I’ve taken a lot of medication over the years, some harsh ones too. I have diabetes and was diagnosed with a fatty liver. I hope this will help in the long run. Great quantity for money, will keep buying in the future. Recommend.
Have turned a few people on to this, great for keeping regular. Had food poisoning and gave it a try, just took one tablet and passed it in record time; was very surprised and happy it worked. If you’ve ever had food poisoning you know what I mean.
We take too much supplements and medications, its extremely tough on your liver. Even protein powder and other multivitamins are taxing on your liver and kidney. This will help your liver and get it to work for you like well oiled machine.
A while ago I was told that I had a spongey liver by doctor. I used to indulge in a lot of drinking in my younger years would be one reason. The second reason and most important was the medicines that I had been on for close to 20 years. The last 2 physicals that I had came out perfect. My doctor asked me what I was taking for my liver problems. I told him it was Milk Thistle. He had heard that it might help, but he never had any patients that actually took it. I would say that it was probably around 6 months before there was any difference. All I can say is that this stuff works great for me. Take a chance, it’s your liver.
I use this product for my 2 aging dogs who previously had imbalanced liver values. Continued use of this supplement, one capsule per day, has corrected those imbalances
I take it daily with meals. Organika is one of my trusted brands.